Turbiscan Stability Index

Shelf-life of products characterized by one number: the TURBISCAN STABILITY INDEX (TSI).

Main advantages

  • Quantifies any type of destabilization
  • A one click calculation
  • Robust, and operator-independent

How does it work?

TSI is a Turbiscan specific parameter developed specially for formulators to rapidly compare and characterize the physical stability of various formulations.

Any destabilization phenomenon happening in a given sample will have an effect on the BackScattering and/or Transmission signal intensities during the aging process. The formulation with the highest intensity variation, is the one to change in the most significant way, thus the least stable.

The TSI calculation, simple but robust concept, sums up the evolution of T or BS light at all measured position (h), based on a scan-to-scan difference, over total sample height (H):

Thus, for each scan, a single TSI value is associated and “Destabilisation kinetics” graphic can be created showing TSI evolution with time. Below a representative example on 4 samples: 3 new formulations (B, C, D) were compared to an old formulation, considered stable (A).

Thanks to the Turbiscan, a quick and global overview of the stability can be established. In a matter of hours, the stability can be evaluated and predicted, days before the changes appear to the naked eye. With a single look at TSI, it is possible to draw conclusions about the most stable formulation.

Here, Sample B offers similar or higher stability than the reference formulation (A). Both Samples C and D are less stable compared to the reference formulation.

Main Advantages

> Considers any type of destabilization

Don't miss any phenomenon taking place in your sample, the algorithm takes any change into account!

> Fully automated

Compute the TSI for all your samples in just one-click after the data acquisition. Rank your samples from the least to most stable automatically.

> Robust and operator-independent

No parameter needed, no settings by the operator requested. If the TSI increases, it's only because the product changes.