RHMAS-AN-18_Platelet lysate gelation

Human platelet lysates are a part of blood donations, which can be used as a cell culture medium, with advantages for proliferation such as human growth factors. However, with the addition of calcium ions (e.g. with cell culture liquids), the lysate forms a gel, which inhibits proper cell proliferation. These gels are very weak and practically not measurable with a normal rheometer. Rheolaser Master measures at rest and without contact, which allows monitoring of the gelation properties even for very weak gels.

Gelation behavior of platelet lysates, control of gelation properties.

File Type: pdf
Categories: Application Note, Bulk Rheology, Diffusing Wave Spectroscopy (MS-DWS), Pharmaceutical, Rheolaser Master
Tags: Gelation, Platelet lysates, Rheolaser Master, Weak gel
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