Colloidal & Physical stability analysis and shelf-life determination are key criteria in formulation studies of dispersion analysis. Turbiscan allows you to have a stability quantification without sample preparation that is up to 1,000x faster than conventional tests. Creaming, sedimentation, agglomeration, aggregation, and coalescence of even highly concentrated formulations are able to be detected, at a very early stage, without dilution or mechanical stress.
Stability kinetics analysis is provided for an efficient and reliable analysis of samples. To help evaluate the overall quality of formulations, the Turbiscan Stability Index can be calculated – quantifying the destabilization with a single number.
No Sample preparation
1,000x faster than conventional tests
Quantification of stability
Turbiscan detects the intensity of both transmitted and backscattered light over the whole tube height named scan. These scans allow direct monitoring of local physical heterogeneities with a vertical resolution down to 20µm. This allows nascent destabilization phenomenon to be detected and monitored over time at different intervals. Scan acquisitions are repeated over time to quantify the evolution of sample destabilization.
Something that also contributes to accelerate stability and shelf life measurement is the Multiple Light Scattering Technology (SMLS). SMLS is an optical technique with high resolution to the smallest variation of particle size and particle concentration, making the ideal technology for stability analysis. It offers the advantage of working from low to high concentration, in native media and is perfectly adapted for working without dilution and on a wide range of particle size : 10nm to 1mm.
The Turbiscan and the SMLS technology complies to several TS and TR documents from the ISO committee such as :
ISO/TR 13097
Guidelines for the characterization of dispersion stability
ISO/TR 18811
Cosmetics – Guidelines on stability testing of cosmetics products
ISO/TS 22107
Dispersibility of solid particles into liquid
ISO/TS 21357
Nanotechnologies – Evaluation of the mean size of nano objects in liquid dispersions by static multiple light scattering (SMLS)
