April 21, 2023

Online Particle Sizing for Raw Materials and Process Screening

Not well defined and most of the time unknown, the dispersibility of a formulation is essential to ensure its required end-use properties. The dispersion’s final quality mostly results from the de-agglomeration/emulsification process occurring in the initial dispersion state. Therefore, formulation scientists must first well disperse particles with the desired particle size and then make sure the product is stable over time.

In a complex operation, dispersibility depends on formulation parameters (raw material choice, media, viscosity…) and the dispersing process (mixing time, applied energy…). In addition, methods for dispersibility characterization usually require strong sample modification (dilution, sampling, external stress), making dispersibility studies long, tedious, and not always reliable.

Therefore two questions arise:
Which particle type or additives are the most suitable for the formulation?
Which mixing type and mixing time to choose?

During this webinar three topics will be covered to answer these questions:
– A first introduction and definition of dispersibility based on the Technical Specification ISO/TS 22107:2021 “Dispersibility of solid particles into a liquid”
– A method to screen the online dispersibility of different raw materials and their affinity within the solvent
– The process conditions to obtain the desired particle size with an online particle size measurement

Fulfilling the ISO recommendations, the Turbiscan DNS based on SMLS (Static Multiple Light Scattering) will be introduced. All the studies are done on native samples without any dilution and online thanks to the unique capabilities of this 2-in-1 platform for fast decision-making.

Discover Turbiscan DNS

Application Note: Raw Material Screening

Application Note: Milling Process Optimization

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