One of the main challenges in formulation and liquid dispersions is to ensure the stability and homogeneity of the product over time. Stability is defined as the ability of a system to resist any change in its properties or appearance due to physical phenomena such as sedimentation, creaming, coalescence, flocculation, or aggregation. These phenomena can affect the performance, safety, and quality of the product, leading to customer dissatisfaction, product recalls, or regulatory issues. Therefore, it is crucial to measure and monitor the stability of formulations and liquid dispersions throughout their development, manufacturing, and storage.
The Turbiscan Stability Index (TSI) is a powerful tool that enables the user to measure and compare the stability of different formulations and liquid dispersions in a fast, reliable, and non-invasive way. The TSI is based on the principle of static multiple light scattering (SMLS), which allows for the detection and quantification of any variation in the concentration or size of the dispersed phase within the sample. The TSI corresponds to the sum of all the variations occurring within the sample in function of time and space and so, The higher the value, the higher the instability of the system.
It can be used to monitor stability evolution over time and to compare the samples’ stability. Thanks to the TSI scale, the TSI value can be correlated to the visual appearance of the sample.
TSI is a valuable and unique parameter that provides the user with a rapid and objective way to measure and compare the stability of formulations and liquid dispersions. It is a widely recognized and must-have tool for any formulator and liquid dispersion specialist who wants to ensure the quality and performance of their products.
This webinar covers a quick introduction of the TSI and its application for stability comparison and prediction.